Road Trips from Los Angeles
The best road trips from Los Angeles are the ones where the drive is doing work — the Pacific Coast Highway curling south toward Laguna, the 101 easing you into Santa Barbara's wine country, the desert run past wind farms to Palm Springs and Joshua Tree. This guide covers the drives behind our six weekend destinations, and what is worth booking at the far end of each.
Los Angeles is unusually spoiled for road trips: ocean in two directions, desert in a third, and a mountain wall that turns any drive into an event. This guide treats the drive as the first act of the weekend rather than the tax on it — the routes, the character of each, the stops the tours themselves pass, and the anchors worth booking before you leave.
All five drives here end at destinations our site compares in full, so the far end of each route links to a page with the bookable layer spelled out.
The coast highway south: Laguna and beyond
The Pacific Coast Highway out of the city is the drive every visitor imagines Angelenos take daily, and southbound is its best direction — the coastline riding along on your right, beach towns thinning from busy to beautiful, until Laguna Beach folds you into its mile of galleries and coves. From there the same road continues toward San Diego if the weekend wants a city at its end.
The bookable layer at the far end suits a road-trip rhythm: a walking food tour through five Laguna kitchens, a surf lesson at the village break, or the whale-watching boats from Newport — the route's one genuine detour, a short drive north of Laguna, where the cruises pass the coastline you just drove.
The Laguna Beach page and the San Diego page cover both ends of this drive.
The coast north: Santa Barbara and wine country
Northbound is the grown-up version: the coastline gives way to the wide agricultural sweep toward Santa Barbara, where the red tiles start and the mountains pinch down to the sea. The town itself is the weekend — walkable, bikeable, oriented by a trolley loop — and the drive continues past it into the Santa Ynez Valley, where the tasting rooms sit among the vines and the wine tours with hotel pickup spare you the scenic-but-illegal part of wine country driving.
For the road-tripper, the two-part structure is the gift: coast on the way up, wine country on the way home, or reversed. The zipline and ranch tours in the valley add the version with adrenaline in it.
Everything bookable along this route is compared on the Santa Barbara page.
The desert run: Palm Springs
East on the 10, the basin empties and the wind farms begin — the towers the Joshua Tree day tour's own route description names as scenery, which tells you how much a part of the drive they are. Palm Springs arrives as an oasis of mid-century low-rise under the sheer wall of Mount San Jacinto, whose tramway turns the drive's ending into an elevation gain of more than a mile in ten minutes.
This is the road trip with a pool at the end of it. Book the tram's late-morning car, the celebrity-homes cart for orientation, and the jeep tour into the San Andreas Fault from Palm Desert for the geology chapter of the drive continued on foot.
The Palm Springs page has the full comparison.
Into the park: Joshua Tree
The last leg of the desert run, or its own trip entirely: the road from Palm Springs to the town of Joshua Tree is a short drive, and inside the park the driving becomes the activity. The main loop road strings Hidden Valley, Skull Rock, Cap Rock and Keys View together with stops measured in minutes and scrambles — country that rewards the audio driving tour's format, a voice in the car that knows which boulder pile is which.
The road-tripper's version of this weekend is the purist's too: car, cooler, park loop, sunset at Keys View, and a soundbath under the stars instead of a drive home. The one-day alternative folds the whole drive and the park into a guided round-trip from Los Angeles with admission and lunch included.
Both versions are compared on the Joshua Tree page.
Book the far end before you drive
Every destination page compares the anchors this guide names — tram cars, audio tours, food walks — with departure points and cancellation terms stated.
See the Joshua Tree AnchorsThe crossing: Newport to Catalina
One route in this guide ends on water. Catalina's weekend begins at the Newport Beach ferry terminal — the drive to the dock yours, the 75-minute crossing the boat's — and the island's car-free logic takes over from the dock. A helicopter transfer from Santa Monica compresses the whole journey to about 25 minutes when the schedule matters. Neither leg is included in any island tour's price, so book the crossing as its own line and treat it as the best opening scene any of these six weekends has.
The Catalina page covers the crossings and the island anchors.
Notes for the driver
Desert arithmetic first: the audio tour's own guidance asks for a litre of water per hour of hiking, and the same conservatism applies to the drive — fuel up earlier than feels necessary, and treat summer desert legs as early-morning business. The tramway listing's 30-degree temperature swing between floor and summit is a useful reminder that these trips change character with elevation fast.
Timing beats routing on every drive here. The coast south clogs on Saturday mornings, the desert rewards the earliest possible start in warm months, and wine country is at its best when the tasting rooms open rather than when they close. Most anchors compared across this site cancel free up to 24 hours before — terms live on each booking page, which is the road-tripper's insurance policy against a morning that starts later than planned.
Pick the road, then the weekend
Five drives, one crossing, six destinations — every one bookable, most cancelable up to 24 hours out.
Compare All Six Destinations